- Calophyllum oil comes from a fruit that grows in Madagascar, southern Africa, islands in the South Pacific and many other tropical islands. It is well known for its properties that accelerate wound healing and new cell growth. Calophyllum is comforting for achy joints, rheumatism, arthritis and sciatica. It's non-irritating to the mucous membranes, making it excellent for sensitive areas on the body. It also helps to heal burns, rashes and insect bites.